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Methotrexate is an antimetabolite medicine, as it impacts cell metabolic rate. It could be recommended for addressing active rheumatoid arthritis, boob cancer, skin psoriasis, and other disorders associated with uncommon and fast growth of cells in the body. This medication can be carried out orally, in addition to injected intramuscularly or intravenously. Methotrexate is most frequently given weekly, unless recommended otherwise by the medical professional.